{Reference Type}: Journal Article
{Title}: Collost Bioplastic Collagen Material for the Treatment of Burns.
{Author}: Budkevich LI;Mirzoyan GV;Gabitov RB;Brazol MA;Salistyj PV;Chikinev YV;Shmyrin AA;Glutkin AV;
{Journal}: Sovrem Tekhnologii Med
{Volume}: 12
{Issue}: 1
{Year}: 2020
暂无{DOI}: 10.17691/stm2020.12.1.12
{Abstract}: The aim of the study was to evaluate the efficacy and safety of the Collost bioplastic material in the treatment of borderline and mosaic burns.
UNASSIGNED: We conducted a prospective multicenter study, which included 94 patients aged 1 to 12 years with thermal skin burns (grade II-III by ICD-10). Patients were divided into four groups. In groups 1-3, various forms of the Collost bioplastic material were used (group 1 - 7% gel, group 2 - membranes, group 3 - powder) in combination with hydrocolloid dressings containing Ag+ ions. Patients of the control group (group 4) underwent the traditional local conservative treatment using hydrocolloid dressings alone. Concomitant therapy was similar in all of the participating centers. The total follow-up period was 4 weeks from the date of burn injury.
UNASSIGNED: On day 14, there were 23 cases (92%) of complete epithelization in group 1, 13 cases (68.4%) - in group 2, 21 cases (78%) - in group 3, and 9 cases (39.1%) - in group 4. The data from groups 1 and 3 significantly differed from those in control (p<0.05). The epithelialization of the burned skin in the Collost groups (7% gel and powder) was on average one week faster compared to the control.
UNASSIGNED: The Collost bioplastic material (in the form of gel or powder) in combination with hydrocolloid dressings can be a functional and inexpensive alternative to autografts in the treatment of borderline and mosaic burns.