{Reference Type}: Case Reports {Title}: An Unusual Case of Genital Lesion: A Vulvar Syringoma. {Author}: Algeri P;Rodella R;Manfredini C;Algeri M; {Journal}: J Family Reprod Health {Volume}: 15 {Issue}: 1 {Year}: Mar 2021 暂无{DOI}: 10.18502/jfrh.v15i1.6080 {Abstract}: Objective: Syringoma is a benign adnexal neoplasm of sweat gland, usually presenting as extra-genital lesions, while vulvar localization is rare. Moreover, syringoma is an uncommon vulvar neoplasms. Case report : A 44-year-old woman with previous diagnosis of duodenal gastrointestinal stromal tumour, underwent a local surgical excision for an isolated, painful, vulvar lesion. The specimen was submitted for histological examination. A vulvar syringoma was diagnosed. Conclusion: We describe this case according on its rarity and atypical presentation as well; therefore, vulvar neoplasms encompass many differential diagnoses, among which the incidence rate of syringoma is very low. Although its rarity, syringoma should be included among the differential diagnosis for vulvar neoplasm.