{Reference Type}: Practice Guideline {Title}: ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part II: Cardiac, surgical, perioperative, operative, and post-operative challenges and management statements. {Author}: Bermudez CA;Crespo MM;Shlobin OA;Cantu E;Mazurek JA;Levine D;Gutsche J;Kanwar M;Dellgren G;Bush EL;Heresi GA;Cypel M;Hadler R;Kolatis N;Franco V;Benvenuto L;Mooney J;Pipeling M;King C;Mannem H;Raman S;Knoop C;Douglas A;Mercier O; {Journal}: J Heart Lung Transplant {Volume}: 40 {Issue}: 11 {Year}: 11 2021 {Factor}: 13.569 {DOI}: 10.1016/j.healun.2021.07.016 {Abstract}: Patients with connective tissue disease (CTD) present unique surgical, perioperative, operative, and postoperative challenges related to the often underlying severe pulmonary hypertension and right ventricular dysfunction. The International Society for Heart and Lung Transplantation-supported consensus document on lung transplantation in patients with CTD standardization addresses the surgical challenges and relevant cardiac involvement in the perioperative, operative, and postoperative management in patients with CTD.