{Reference Type}: Journal Article {Title}: Helicobacter pylori infection: place of serological and cultural diagnostics in clinical guidelines. {Author}: Kornoukhova LA;Emanuel VL;Denisov NL;Nikonov EL; {Journal}: Klin Lab Diagn {Volume}: 66 {Issue}: 8 {Year}: Aug 2021 13 暂无{DOI}: 10.51620/0869-2084-2021-66-8-496-501 {Abstract}: The purpose of this work was to familiarize doctors with the methods and significance of serological and cultural diagnostics of H. pylori infection on the example of the test for diagnosing the state of the gastric mucosa «Gastropanel». Blood serum tests were performed for 1057 patients and 122 healthy people aged 18-64 years: pepsinogen I (PG I), pepsinogen II (PG II), gastrin-17 (G-17), basal/stimulated), antibodies (IgGHp) to H. pylori (Biohit Oyj, Finland). The medians of the studied group indicators did not exceed the reference intervals. 398 (34%) patients have negative H. pylori status (IgGHp-). 275 (26%) patients with serum PG I≤70 mcg/ml were identified. The ratio of PG I/II≤3 in 84 (8%), 36 of them (43% of the group PG I/II≤3) - IgGHp-.