{Reference Type}: Journal Article {Title}: Three-dimensional facial hard tissue symmetry in a healthy Caucasian population group: a systematic review. {Author}: Morgan N;Suryani I;Shujaat S;Jacobs R; {Journal}: Clin Oral Investig {Volume}: 25 {Issue}: 11 {Year}: Nov 2021 {Factor}: 3.606 {DOI}: 10.1007/s00784-021-04126-w {Abstract}: OBJECTIVE: The aim of this study was to quantify the symmetry of the facial hard tissue structures using three-dimensional radiographic imaging modalities in a normal Caucasian population group.
METHODS: Electronic literature search was conducted in the following databases: PubMed, Embase, Web of Science, and Cochrane Library up to February 2021. The studies assessing symmetry of facial bones using computed tomography (CT) and cone beam CT were included.
RESULTS: The initial search revealed 8811 studies. Full-text analysis was performed on 33 studies. Only 10 studies were found eligible based on the inclusion criteria. The qualitative analysis revealed that a significant variability existed in relation to the methodologies applied for symmetry quantification.
CONCLUSIONS: The current review suggested that the overall relative symmetry of the normal Caucasian population group varied depending on the skeletal structure being assessed; however, majority of the observations showed a symmetry within the range of 1 mm without any significant difference between left and right sides.
CONCLUSIONS: The quantification of facial hard tissue structure symmetry is vital for the diagnosis and treatment planning of orthodontic and/or maxillofacial surgical procedures. Prospero registration number CRD42020169908.