{Reference Type}: Journal Article
{Title}: Genetic characteristics of HIV-1 CRF06_cpx and CRF56_cpx strains isolated in Guangzhou, China.
{Author}: Lan Y;Li L;Cai W;Li J;Deng X;Li F;Lei C;Hu F;Tang X;
{Journal}: Arch Virol
{Volume}: 166
{Issue}: 10
{Year}: Oct 2021
{Factor}: 2.685
{DOI}: 10.1007/s00705-021-05198-5
{Abstract}: Strains of the HIV-1 circulating recombinant forms (CRFs) 06_cpx and 56_cpx were identified for the first time in Guangzhou, China. The nearly full-length genome (NFLG) sequence was amplified, and the PCR products were sequenced by the Sanger method. The CRF06_cpx and CRF56_cpx strains were identified using the Basic Local Alignment Search Tool (BLAST) and confirmed by neighbour-joining (NJ) phylogenetic analysis. Additionally, these strains were found to contain transmitted drug resistance mutations that have little effect on first-line efavirenz (EFV)-based treatment. Genetic analysis of the detailed sequence data will provide more information on the HIV-1 epidemic in China.