{Reference Type}: Journal Article
{Title}: Mechanisms of Caloric Restriction-Mediated Stress-Resistance in Acute Kidney Injury.
{Author}: Koehler FC;Späth MR;Hoyer-Allo KJR;Müller RU;
{Journal}: Nephron
{Volume}: 0
{Issue}: 0
{Year}: Aug 2021 2
{Factor}: 3.457
{DOI}: 10.1159/000517733
{Abstract}: Caloric restriction (CR)-mediated organ protection has been shown to be extremely efficient in rodent models of acute kidney injury (AKI). Limited understanding of the underlying mechanisms paired with a risk of malnourishment and feasibility problems has hindered the translation of this immense potential to the patient setting. In this mini-review, the current mechanistic concepts of CR-mediated stress-resistance as potential key targets for renal protection in AKI will be highlighted.