{Reference Type}: Journal Article
{Title}: Viridans Group Streptococci in Pediatric Leukemia and Stem Cell Transplant: Review of a Risk-stratified Guideline for Empiric Vancomycin in Febrile Neutropenia.
{Author}: Ruhayel SD;Foley DA;Hamilton K;Ferguson P;Kotecha RS;Bowen AC;Yeoh DK;
{Journal}: Pediatr Infect Dis J
{Volume}: 40
{Issue}: 9
{Year}: 09 2021 1
{Factor}: 3.806
{DOI}: 10.1097/INF.0000000000003210
{Abstract}: Viridans group streptococci (VGS) are an important cause of sepsis in immunosuppressed children. We reviewed the effectiveness of risk-stratified addition of vancomycin to empiric febrile neutropenia therapy among 107 children with leukemia or undergoing an allogeneic transplant. Of 19 VGS bacteremia episodes, 78.9% were susceptible to risk-stratified antibiotics including 100% from high-risk patients. All blood cultures were flagged positive within 24 hours.