{Reference Type}: Case Reports
{Title}: A case of reversible cerebral vasoconstriction syndrome associated with anti-phospholipid antibody syndrome and systemic lupus erythematosus.
{Author}: Shima A;Maki T;Mimura N;Yamashita H;Emoto N;Yoshifuji H;Takahashi R;
{Journal}: eNeurologicalSci
{Volume}: 24
{Issue}: 0
{Year}: Sep 2021
暂无{DOI}: 10.1016/j.ensci.2021.100351
{Abstract}: The pathomechanisms and treatment strategy for rare presentations of reversible cerebral vasoconstriction syndrome (RCVS) with anti-phospholipid syndrome (APS) remain to be determined. We report a 67-year-old woman with APS who presented with ischemic stroke due to RCVS. She was treated with low-dose cilostazol and lomerizine hydrochloride, which resulted in functional improvement and recovery of vasoconstriction within 12 weeks. Her plasma endothelin-1 level was decreased after relief of vasoconstriction, compared with the pre-treatment condition. Increased plasma endothelin-1 may be related to the underlying pathomechanism of RCVS with APS, against which cilostazol and lomerizine hydrochloride could be effective.