{Reference Type}: Journal Article
{Title}: Zebrafish as a New Model to Study the Crosstalk between Tumor and Host Metabolism.
{Author}: Montal E;White RM;
{Journal}: Trends Cancer
{Volume}: 7
{Issue}: 8
{Year}: 08 2021
{Factor}: 19.161
{DOI}: 10.1016/j.trecan.2021.06.006
{Abstract}: The mechanism of metabolic crosstalk between different tissues in the host remains poorly understood but is likely to play important roles in tumor growth and cachexia. A recent study from Naser, Jackstadt, et al. utilizes isotope tracing in a zebrafish melanoma model and finds that tumors secrete alanine into circulation, which is taken up by the liver and used for gluconeogenesis.