{Reference Type}: Journal Article
{Title}: Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study.
{Author}: Escrihuela-Vidal F;López-Cortés LE;Escolà-Vergé L;De Alarcón González A;Cuervo G;Sánchez-Porto A;Fernández-Hidalgo N;Luque R;Montejo M;Miró JM;Goenaga MÁ;Muñoz P;Valerio M;Ripa M;Sousa-Regueiro D;Gurguí M;Fariñas-Alvarez MC;Mateu L;García Vázquez E;Gálvez-Acebal J;Carratalà J; ;
{Journal}: Open Forum Infect Dis
{Volume}: 8
{Issue}: 6
{Year}: Jun 2021
{Factor}: 4.423
{DOI}: 10.1093/ofid/ofab163
{Abstract}: <B>UNASSIGNED: </B>Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption.<BR><B>UNASSIGNED: </B>We performed a retrospective analysis of prospectively collected data from consecutive patients with definite SAG endocarditis in 28 centers in Spain and Italy. A comparison between cases due to SAG endocarditis and viridans group streptococci (VGS) or Streptococcus gallolyticus group (SGG) was performed in a 1:2 matched analysis.<BR><B>UNASSIGNED: </B>Of 5336 consecutive cases of definite endocarditis, 72 (1.4%) were due to SAG and matched with 144 cases due to VGS/SGG. SAG endocarditis was community acquired in 64 (88.9%) cases and affected aortic native valve in 29 (40.3%). When comparing SAG and VGS/SGG endocarditis, no significant differences were found in septic shock (8.3% vs 3.5%, P = .116); valve disorder, including perforation (22.2% vs 18.1%, P = .584), pseudoaneurysm (16.7% vs 8.3%, P = .108), or prosthesis dehiscence (1.4% vs 6.3%, P = .170); paravalvular complications, including abscess (25% vs 18.8%, P = .264) and intracardiac fistula (5.6% vs 3.5%, P = .485); heart failure (34.7% vs 38.9%, P = .655); or embolic events (41.7% vs 32.6%, P = .248). Indications for surgery (70.8% vs 70.8%; P = 1) and mortality (13.9% vs 16.7%; P = .741) were similar between groups.<BR><B>UNASSIGNED: </B>SAG endocarditis is an infrequent but serious condition that presents a prognosis similar to that of VGS/SGG.