{Reference Type}: Journal Article
{Title}: Surgical treatment strategy for locally advanced colorectal cancer with abdominal wall invasion.
{Author}: Song Z;Yang D;Song H;Dong W;Wu J;Yang J;Gu Y;
{Journal}: Ann Transl Med
{Volume}: 9
{Issue}: 10
{Year}: May 2021
{Factor}: 3.616
{DOI}: 10.21037/atm-21-2094
{Abstract}: <B>UNASSIGNED: </B>The incidence of abdominal wall metastasis from colorectal cancer (CRC) is very low, but it has a poor prognosis. Despite the advances in radiotherapy, chemotherapy, and targeted therapy, patient prognosis has not improved significantly. Through surgical treatment, some patients with locally advanced CRC with abdominal wall invasion can achieve tumor-free survival or an improved quality of life.<BR><B>UNASSIGNED: </B>The clinical data of 15 patients in our department from January 2015 to January 2020 were retrospectively analyzed. All patients underwent preoperative three-dimensional reconstruction of the tumor and abdominal wall after discussion with a multidisciplinary team (MDT). Patient information, including tumor size, defect size, operation time, intraoperative bleeding, hospital stay, and other factors, was collected.<BR><B>UNASSIGNED: </B>All 15 patients underwent resection followed by reconstruction for locally advanced CRC with abdominal wall invasion. The average tumor area and abdominal wall defects were 98.13±71.70 and 270.07±101.95 cm2, respectively; and accurate abdominal wall classification and zoning were obtained for all patients. The average operation time was 431.7±189.2 min, and the average blood loss was 513.3±244.6 mL. The recurrence rates in the incisional hernia and abdominal wall were 6.0% and 13.3%, respectively. The patient survival rate was 87.7%.<BR><B>UNASSIGNED: </B>Surgical treatment of locally advanced CRC with abdominal wall invasion is feasible, but requires accurate and comprehensive preoperative evaluation.