{Reference Type}: Journal Article {Title}: Treatment of Epilepsy Associated with Common Chromosomal Developmental Diseases. {Author}: Budisteanu M;Jurca C;Papuc SM;Focsa I;Riga D;Riga S;Jurca A;Arghir A; {Journal}: Open Life Sci {Volume}: 15 {Issue}: 0 {Year}: 2020 {Factor}: 1.311 {DOI}: 10.1515/biol-2020-0003 {Abstract}: Chromosomal diseases are heterogeneous conditions with complex phenotypes, which include also epileptic seizures. Each chromosomal syndrome has a range of specific characteristics regarding the type of seizures, EEG findings and specific response to antiepileptic drugs, significant in the context of the respective genetic etiology. Therefore, it is very important to know these particularities, in order to avoid an exacerbation of seizures or some side effects. In this paper we will present a review of the epileptic seizures and antiepileptic treatment in some of the most common chromosomal syndromes.