{Reference Type}: Journal Article {Title}: A nano-integrated microfluidic biochip for enzyme-based point-of-care detection of creatinine. {Author}: Li J;Li Z;Dou Y;Su J;Shi J;Zhou Y;Wang L;Song S;Fan C; {Journal}: Chem Commun (Camb) {Volume}: 57 {Issue}: 38 {Year}: May 2021 11 {Factor}: 6.065 {DOI}: 10.1039/d1cc00825k {Abstract}: A nano-integrated portable enzymatic microfluidic electrochemical biochip was developed for single-step point-of-care testing of creatinine. The biochip could automatically eliminate a lot of interferences from practical biological samples and enzymatic intermediate products. Gold nanostructure- and carbon nanotube-based screen-printed carbon electrodes were integrated into microfluidic structures to improve the detection performance for creatinine. The microfluidic electrochemical biochip holds promise to become a practical device for medical diagnosis, especially POCT.