{Reference Type}: Journal Article {Title}: Feasibility and long-term safety of Ho:YAG laser lithotripsy in broncholithiasis patients. {Author}: Cheng Y;Wang G;Zhang W;Zhang H;Wang X; {Journal}: BMC Pulm Med {Volume}: 21 {Issue}: 1 {Year}: Mar 2021 10 {Factor}: 3.32 {DOI}: 10.1186/s12890-021-01407-8 {Abstract}: BACKGROUND: Treatment of broncholithiasis is complex, especially in the case of a large or transbronchial broncholith. Holmium-yttrium aluminum garnet (Ho:YAG) laser lithotripsy may be a useful treatment in broncholithiasis; however, as it is not yet common practice, the optimal parameters are unknown.
METHODS: We performed a single-center retrospective analysis of the clinical data of 13 broncholithiasis patients who underwent Ho:YAG laser lithotripsy from May 2012 to October 2018.
RESULTS: For the 13 patients (2 males and 11 females), Ho:YAG laser lithotripsy was performed 17 times, in total. All procedures were performed under general anesthesia with rigid bronchoscopy. We initially set the Ho:YAG laser to a pulse frequency of 5 Hz and a pulse energy of 0.8 J, gradually increasing these as required. The pulse frequency range we employed was 5-15 Hz, and the pulse energy range was 0.8-1.6 J. All broncholiths were successfully extracted after lithotripsy, and all symptoms improved. Hemoptysis, bronchial esophageal fistula, and pneumonia were the most common complications; however, there were no long-term complications.
CONCLUSIONS: Ho:YAG laser lithotripsy is an effective and safe treatment for broncholithiasis, over a long-term follow up.