{Reference Type}: Case Reports
{Title}: Case of placental insufficiency and premature delivery in a Fontan pregnancy: physiological insights and considerations on risk stratification.
{Author}: Ordoñez MV;Biglino G;Caputo M;Kelly B;Mohan A;Trinder J;Curtis SL;
{Journal}: Open Heart
{Volume}: 8
{Issue}: 1
{Year}: 02 2021
暂无{DOI}: 10.1136/openhrt-2019-001211
{Abstract}: The coexistence of two complex physiologies such as Fontan and pregnancy is still not fully understood. We aim to add a unique and essential knowledge to help our colleagues in the management of Fontan patients that undergo pregnancy as well as the fetus and the placenta perfusion.
We analyse the coexistence of Fontan and pregnancy physiology on a complex case of a woman with hypoplastic left heart syndrome palliated with a univentricular repair who became pregnant, delivered very prematurely and had atypical placental findings.
Histopathological analysis of the placenta could help us to refine the understanding of Fontan physiology adaptation during pregnancy, predict women and fetal outcomes as well as to plan a better pre-pregnancy status. However, further evidence is needed in order to reach a more solid and unified conclusion.