{Reference Type}: Case Reports
{Title}: Hallux rigidus treated with adipose-derived mesenchymal stem cells: A case report.
{Author}: Braile A;Toro G;De Cicco A;Cecere AB;Zanchini F;Schiavone Panni A;
{Journal}: World J Orthop
{Volume}: 12
{Issue}: 1
{Year}: Jan 2021 18
暂无{DOI}: 10.5312/wjo.v12.i1.51
{Abstract}: <B>BACKGROUND: </B>First metatarsophalangeal joint arthritis (FMTPA), also known as hallux rigidus, is the most frequent degenerative disease of the foot. Diagnosis is made through both clinical and radiological evaluation. Regenerative medicine showed promising results in the treatment of early osteoarthritis. The aim of the present study was to report the results of a case of FMTPA treated with the injection of autologous adipose-derived mesenchymal stem cells.<BR><B>METHODS: </B>A gentleman of 50 years of age presented with a painful hallux rigidus grade 2 resistant to any previous conservative treatment (including nonsteroidal anti-inflammatory drugs and hyaluronic acid injections). An injection of autologous adipose-derived mesenchymal stem cells into the first metatarsophalangeal joint was performed. No adverse events were reported, and both function and pain scales improved after 9 mo of follow-up.<BR><B>CONCLUSIONS: </B>The FMTP joint injection of mesenchymal stem cells improved symptoms and function in our patient with FMTPA at 9 mo of follow-up.