{Reference Type}: Journal Article
{Title}: Catheter-related blood stream infections: prevalence, risk factors and antimicrobial resistance pattern.
{Author}: Pandit P;Sahni AK;Grover N;Dudhat V;Das NK;Biswas AK;
{Journal}: Med J Armed Forces India
{Volume}: 77
{Issue}: 1
{Year}: Jan 2021
暂无{DOI}: 10.1016/j.mjafi.2019.07.002
{Abstract}: UNASSIGNED: Intravascular devices have significant potential for producing iatrogenic diseases resulting in catheter-related blood stream infections (CRBSIs). A study was undertaken to find the prevalence of CRBSI among patients in acute wards and to analyze the associated risk factors, causative pathogens with their antibiotic susceptibility (ABST) patterns.
UNASSIGNED: Randomly ten days per month were chosen, for a period of two years. All the acute wards patients who were on indwelling blood catheters were identified. Those fulfilling the CRBSI criteria were further worked up for confirmation of diagnosis by differential time to positivity. The catheter tip was cultured by Maki's semiquantitative method. ABST of the isolates obtained was performed by Kirby-Bauer disk diffusion method.
UNASSIGNED: The prevalence of CRBSI was found to be 39.25% with the most common organism isolate being Serratia marcescens (23.81%). The immunocompromised status of the patients and catheterisation time were significant risk factors. Methicillin resistance was found to be 33.33% in coagulase-negative staphylococci. The resistance to vancomycin among the Entercoccus faecium isolates was found to be 33.33%. Among the gram negatives, resistance to aminoglycosides, fluoroquinolones and third-generation cephalosporins was high.
UNASSIGNED: The study highlights the importance of regular surveillance programs, an efficient infection control program, strict adherence to antiseptic measures and use of a rational antibiotic policy for the early diagnosis and better management of CRBSI.