{Reference Type}: Journal Article
{Title}: Chiral Self-sorting of Giant Cubic [8+12] Salicylimine Cage Compounds.
{Author}: Wagner P;Rominger F;Zhang WS;Gross JH;Elbert SM;Schröder RR;Mastalerz M;
{Journal}: Angew Chem Int Ed Engl
{Volume}: 60
{Issue}: 16
{Year}: Apr 2021 12
{Factor}: 16.823
{DOI}: 10.1002/anie.202016592
{Abstract}: Chiral self-sorting is intricately connected to the complicated chiral processes observed in nature and no artificial systems of comparably complexity have been generated by chemists. However, only a few examples of purely organic molecules have been reported so far, where the self-sorting process could be controlled. Herein, we describe the chiral self-sorting of large cubic [8+12] salicylimine cage compounds based on a chiral TBTQ precursor. Out of 23 possible cage isomers only the enantiopure and a meso cage were observed to be formed, which have been unambiguously characterized by single crystal X-ray diffraction. Furthermore, by careful choice of solvent the formation of meso cage could be controlled. With internal diameters of din =3.3-3.5 nm these cages are among the largest organic cage compounds characterized and show very high specific surface areas up to approx. 1500 m2  g-1 after desolvation.