{Reference Type}: Case Reports
{Title}: Primary cutaneous malignant melanoma in Rett syndrome: Report of a case with nuclear features resembling herpes simplex virus cytopathic effects-a hitherto unrecognized morphological variant.
{Author}: Petkar MA;Rodrigo T;
{Journal}: J Cutan Pathol
{Volume}: 48
{Issue}: 7
{Year}: Jul 2021
{Factor}: 1.458
{DOI}: 10.1111/cup.13943
{Abstract}: Rett syndrome (RTT) is a progressive neurological disorder, affecting females with mutations in the X-linked gene methyl-CpG-binding protein 2 (MECP2). While MECP2 has been implicated in cancers of the breast, colon, and prostrate, cancer in patients with RTT is rare. We present a case of malignant melanoma in a patient with RTT, which additionally, displayed hitherto undescribed nuclear features, resembling herpes simplex virus cytopathic effects.