{Reference Type}: Case Reports {Title}: Severe cortical damage associated with COVID-19 case report. {Author}: Zombori L;Bacon M;Wood H;Chatterjee F;Venkateswaran R;Lampariello S;Yoong M; {Journal}: Seizure {Volume}: 84 {Issue}: 0 {Year}: Jan 2021 {Factor}: 3.414 {DOI}: 10.1016/j.seizure.2020.11.014 {Abstract}: Symptoms of COVID-19, as reported during the SARS-CoV-2 pandemic in 2019-2020, are primarily respiratory and gastrointestinal, with sparse reports on neurological manifestations. We describe the case of a 17-year old female with Cornelia de Lange syndrome and well controlled epilepsy, who sustained significant cortical injury during a COVID-19 associated multi-inflammatory syndrome.