{Reference Type}: Case Reports
{Title}: Prosthetic graft replacement of a large subclavian aneurysm in a child with Loeys-Dietz syndrome: a case report.
{Author}: Sobh M;Voges I;Attmann T;Scheewe J;
{Journal}: Eur Heart J Case Rep
{Volume}: 4
{Issue}: 5
{Year}: Oct 2020
暂无{DOI}: 10.1093/ehjcr/ytaa163
{Abstract}: <B>UNASSIGNED: </B>Loeys-Dietz syndrome (LDS) is a genetic connective tissue disorder, which is characterized by rapid development of aortic and peripheral arterial aneurysms. Loeys-Dietz syndrome has some overlapping phenotypic features with other inherited aortopathies such as Marfan syndrome. However, LDS has a more aggressive vascular course with patient morbidity and mortality occurring at an early age.<BR><B>UNASSIGNED: </B>We present the rare case of an 11-year-old girl with LDS who underwent valve sparing aortic root replacement at the age of 2.9 years with good results. She had routine follow-up cardiovascular magnetic resonance imaging and was found to have a large aneurysm of the right subclavian artery. After multidisciplinary team discussion, successful surgical resection with prosthetic graft replacement of the right subclavian artery was performed.<BR><B>UNASSIGNED: </B>This case illustrates that large aneurysms of aortic branches can already develop in childhood and underlines the need for frequent follow-ups including cross-sectional imaging and multidisciplinary team management.