{Reference Type}: Journal Article
{Title}: The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline.
{Author}: Rochwerg B;Einav S;Chaudhuri D;Mancebo J;Mauri T;Helviz Y;Goligher EC;Jaber S;Ricard JD;Rittayamai N;Roca O;Antonelli M;Maggiore SM;Demoule A;Hodgson CL;Mercat A;Wilcox ME;Granton D;Wang D;Azoulay E;Ouanes-Besbes L;Cinnella G;Rauseo M;Carvalho C;Dessap-Mekontso A;Fraser J;Frat JP;Gomersall C;Grasselli G;Hernandez G;Jog S;Pesenti A;Riviello ED;Slutsky AS;Stapleton RD;Talmor D;Thille AW;Brochard L;Burns KEA;
{Journal}: Intensive Care Med
{Volume}: 46
{Issue}: 12
{Year}: 12 2020
{Factor}: 41.787
{DOI}: 10.1007/s00134-020-06312-y
{Abstract}: High flow nasal cannula (HFNC) is a relatively recent respiratory support technique which delivers high flow, heated and humidified controlled concentration of oxygen via the nasal route. Recently, its use has increased for a variety of clinical indications. To guide clinical practice, we developed evidence-based recommendations regarding use of HFNC in various clinical settings.<BR>We formed a guideline panel composed of clinicians, methodologists and experts in respiratory medicine. Using GRADE, the panel developed recommendations for four actionable questions.<BR>The guideline panel made a strong recommendation for HFNC in hypoxemic respiratory failure compared to conventional oxygen therapy (COT) (moderate certainty), a conditional recommendation for HFNC following extubation (moderate certainty), no recommendation regarding HFNC in the peri-intubation period (moderate certainty), and a conditional recommendation for postoperative HFNC in high risk and/or obese patients following cardiac or thoracic surgery (moderate certainty).<BR>This clinical practice guideline synthesizes current best-evidence into four recommendations for HFNC use in patients with hypoxemic respiratory failure, following extubation, in the peri-intubation period, and postoperatively for bedside clinicians.