{Reference Type}: Journal Article
{Title}: Clinical course of COVID-19 among immunocompromised children: a clinical case series.
{Author}: El Dannan H;Al Hassani M;Ramsi M;
{Journal}: BMJ Case Rep
{Volume}: 13
{Issue}: 10
{Year}: Oct 2020 31
暂无{DOI}: 10.1136/bcr-2020-237804
{Abstract}: Infection with SARS-CoV-2 represents a great source of concern and a new threat for immunocompromised patients. Limited studies are available on COVID-19 in immunocompromised children. This case series aimed to evaluate the clinical and laboratory characteristics, management and outcomes of COVID-19 in five children immunocompromised due to different underlying conditions. All had mild symptoms or were asymptomatic at presentation. All had a benign course of illness. No changes or delays in their treatment regimens occurred, and none experienced a relapse of the original disease, developed severe COVID-19 or died. However, these cases showed a prolonged duration of virus shedding. This report suggests that immunocompromised paediatric patients may not be at a higher risk of developing severe COVID-19. However, further studies are required to elaborate on the pathogenesis of COVID-19 in this vulnerable group.