{Reference Type}: Clinical Trial {Title}: A comparison of the effects of Two suture materials on isthmocele formation: A cohort study. {Author}: Hosseini R;Mansoorli S;Pirjani R;Eslamian L;Rabiee M; {Journal}: J Gynecol Obstet Hum Reprod {Volume}: 50 {Issue}: 4 {Year}: Apr 2021 {Factor}: 2.156 {DOI}: 10.1016/j.jogoh.2020.101933 {Abstract}: OBJECTIVE: Cesarean scar defects (CSD) are a problem that may lead to complications and excessive cost. The optimal way to suture the uterus is a matter of debate. The aim of this study was to evaluate the effect of two suture materials on cesarean scar niches.
METHODS: This was a cohort study that allocated women into two groups: uterotomy closure with vicryl or catgut sutures. Transvaginal ultrasound (TVUS) was performed six months after the cesarean section (CS) to assess the scar.
RESULTS: Totally, 250 patients enrolled in this study. After six months, 20 (18.2 %) patients in the catgut suture group and 13 (9.3 %) patients in the vicryl group had isthmocele according to their sonography reports. The prevalence of isthmocele was higher in the catgut group (p = 0.03). The residual myometrial thickness was greater in the vicryl group (4.98 cm ± 2.18) compared to the catgut suture group (3.70 cm ± 1.50; p = 0.001). The prevalence of postoperative gynecological sequelae such as postmenstrual spotting and pain were similar between the two groups.
CONCLUSIONS: Vicryl sutures were associated with a lower risk of CSD formation in comparison with catgut sutures.