{Reference Type}: Journal Article
{Title}: Sea Cucumber Derived Type I Collagen: A Comprehensive Review.
{Author}: Senadheera TRL;Dave D;Shahidi F;
{Journal}: Mar Drugs
{Volume}: 18
{Issue}: 9
{Year}: Sep 2020 18
{Factor}: 6.085
{DOI}: 10.3390/md18090471
{Abstract}: Collagen is the major fibrillar protein in most living organisms. Among the different types of collagen, type I collagen is the most abundant one in tissues of marine invertebrates. Due to the health-related risk factors and religious constraints, use of mammalian derived collagen has been limited. This triggers the search for alternative sources of collagen for both food and non-food applications. In this regard, numerous studies have been conducted on maximizing the utilization of seafood processing by-products and address the need for collagen. However, less attention has been given to marine invertebrates and their by-products. The present review has focused on identifying sea cucumber as a potential source of collagen and discusses the general scope of collagen extraction, isolation, characterization, and physicochemical properties along with opportunities and challenges for utilizing marine-derived collagen.