{Reference Type}: Letter {Title}: Comment on: "The treatment of sarcoptic mange in wildlife: a systematic review". {Author}: Moroni B;Valldeperes M;Serrano E;López-Olvera JR;Lavín S;Rossi L; {Journal}: Parasit Vectors {Volume}: 13 {Issue}: 1 {Year}: Sep 2020 15 {Factor}: 4.047 {DOI}: 10.1186/s13071-020-04347-0 {Abstract}: This letter comments on the article "The treatment of sarcoptic mange in wildlife: a systematic review" published in Parasites & Vectors 2019, 12:99, and discusses the limitations in the use of endectocides for scabies control in free-ranging wildlife. The ecological impact and drug resistance to ivermectin are also discussed. In our view, scabies control in free-ranging wildlife should be based preferably on population management measures, and whether to apply individual treatments to free-ranging populations should be considered very carefully and avoided where not absolutely warranted.