{Reference Type}: Journal Article
{Title}: Multidisciplinary Management of the Adverse Effects of Apremilast.
{Author}: Daudén Tello E;Alonso Suárez J;Beltrán Catalán E;Blasco Maldonado C;Herrero Manso MC;Jiménez Morales A;Marín-Jiménez I;Martín-Arranz MD;García-Merino A;Porta Etessam J;Rodríguez-Sagrado MA;Rosas Gómez de Salazar J;Trujillo Martín E;Salgado-Boquete L;
{Journal}: Actas Dermosifiliogr (Engl Ed)
{Volume}: 112
{Issue}: 2
{Year}: Feb 2021
暂无{DOI}: 10.1016/j.ad.2020.08.007
{Abstract}: We present a series of general and specific recommendations based on pathophysiologic considerations for managing the most common adverse effects of apremilast that lead to treatment discontinuation: diarrhea, nausea, and headache. The recommendations are based on a review of the literature and the experience of a multidisciplinary team of 14 experts including dermatologists, rheumatologists, neurologists, gastroenterologists, pharmacists, and nurses. We propose a series of simple algorithms that include clinical actions and suggestions for pharmacologic treatment. The adverse effects of apremilast can be managed from a multidisciplinary approach. The purpose of optimizing management is to bring clinical benefits to patients.