{Reference Type}: Journal Article {Title}: Evaluation of the relation between Lens Opacities Classification System III grading and nuclear size by direct measurement. {Author}: Kulkarni C; {Journal}: Taiwan J Ophthalmol {Volume}: 10 {Issue}: 2 {Year}: Apr-Jun 2020 暂无{DOI}: 10.4103/tjo.tjo_19_19 {Abstract}: BACKGROUND: Although relation between Lens Opacities Classification System III (LOCS III) and nuclear density is established, no data are available about nuclear size at different LOCS III grades.
OBJECTIVE: The aim of this study is to evaluate the relation between LOCS III grading of nuclear opacity obtained preoperatively and the size of the nucleus obtained during cataract surgery.
METHODS: This was a prospective observational study carried out in a hospital attached to medical college.
METHODS: Patients who underwent manual small-incision cataract surgery or extra-large temporal tunnel cataract extraction and gave consent were included in this study. Institutional Ethics Committee clearance was taken for the study. Preoperative LOCS III grading was obtained at slit-lamp biomicroscope. Ocular dimensions were obtained by preoperative immersion biometry. The thickness and diameter of the nucleus obtained by extraction were measured up to 10 μ accuracy. Data were analyzed for the change in nuclear thickness, nuclear diameter, age, lens thickness, and anterior chamber depth in relation to the LOCS III grade of the nucleus.
METHODS: Statistical analysis used in this study was one-way ANOVA, mean, and range.
RESULTS: There was a significant increase (P < 0.05) in nuclear thickness, nuclear diameter, and age with increasing LOCS III grade of the nucleus. The change in nuclear size was linear between Grades 1 and 4. The nuclear size did not increase between Grades 4 and 5. It increased steeply from Grade 5 to Grade 6.9.
CONCLUSIONS: LOCS III grading of the nucleus can be utilized for determining the nuclear thickness and diameter preoperatively. These data can be helpful in adjusting machine parameters during phacoemulsification.