{Reference Type}: Journal Article {Title}: Speckle Tracking Echocardiography in Hypertensive Pregnancy Disorders: A Systematic Review. {Author}: Moors S;van Oostrum NHM;Rabotti C;Long X;Westerhuis MEMH;Kemps HMC;Oei SG;van Laar JOEH; {Journal}: Obstet Gynecol Surv {Volume}: 75 {Issue}: 8 {Year}: Aug 2020 {Factor}: 3.015 {DOI}: 10.1097/OGX.0000000000000811 {Abstract}: UNASSIGNED: Hypertensive pregnancy disorders (HPDs) are associated with an increased risk of long-term cardiovascular disease. Speckle tracking echocardiography (STE) might be useful in the early detection of preclinical cardiac changes in women with HPDs.
UNASSIGNED: The aim of this study was to study whether STE is a suitable method to detect differences in cardiac function in pregnant women with HPD compared with normotensive pregnant women or between women with a history of a pregnancy complicated by HPD compared with women with a history of an uncomplicated pregnancy.
UNASSIGNED: The databases Medline, EMBASE, and Central were systematically searched for studies comparing cardiac function measured with STE in pregnant women with HPD or women with a history of HPD and women with a history of normotensive pregnancies.
UNASSIGNED: The search identified 16 studies, including 870 women with a history of HPD and 693 normotensive controls. Most studies during pregnancy (n = 12/13) found a decreased LV-GLS (left ventricular global longitudinal strain) in HPD compared with normotensive pregnant controls. LV-GRS (left ventricular global radial strain) and LV-GLCS (left ventricular global circumferential strain) are decreased in women with early-onset and severe preeclampsia. Women with a history of early-onset preeclampsia show lasting myocardial changes, with significantly decreased LV-GLS, LV-GLCS, and LV-GRS.
UNASSIGNED: LV-GLS is significantly decreased in pregnant women with HPD compared with normotensive pregnant women. Other deformation values show a significant decrease in women with severe or early-onset preeclampsia, with lasting myocardial changes after early-onset preeclampsia.