{Reference Type}: Journal Article
{Title}: Very Late-Onset Systemic Lupus Erythematosus as Unusual Cause of Reversible Functional and Cognitive Impairments in an Octogenarian Patient.
{Author}: de Montjoye S;Boland B;Van Raemdonck J;Houssiau FA;
{Journal}: Eur J Case Rep Intern Med
{Volume}: 7
{Issue}: 8
{Year}: 2020
暂无{DOI}: 10.12890/2020_001570
{Abstract}: While functional decline is a common syndrome in geriatric medicine, the diagnosis of the underlying disease can be complex. We present a case of very late-onset systemic lupus erythematosus with fever, arthritis, lymphadenopathy, sicca syndrome, pleurisy, renal impairment and reversible functional and cognitive impairments. Prompt improvement was observed on prednisolone and hydroxychloroquine.
UNASSIGNED: Systemic lupus erythematosus (SLE) rarely occurs in octogenarian patients.In such oldest old patients, SLE may predominantly present with subacute cognitive and functional impairments.Low-dose treatment (prednisolone 7.5 mg/day and hydroxychloroquine 5 mg/kg/day) can reverse all SLE manifestations within 1 month.