{Reference Type}: Case Reports
{Title}: Six cases of Solobacterium moorei isolated alone or in mixed culture in Hungary and comparison with previously published cases.
{Author}: Sárvári KP;Sántha D;Kovács R;Körmöndi S;Pető Z;Vereb T;Sztanó B;
{Journal}: Anaerobe
{Volume}: 65
{Issue}: 0
{Year}: Oct 2020
{Factor}: 2.837
{DOI}: 10.1016/j.anaerobe.2020.102241
{Abstract}: Solobacterium moorei is a strict anaerobic gram-positive rod. It is found in the human microbiota in different parts of the body, but it also appears to be an opportunistic pathogen in some infectious processes. We describe six cases of severe infections identified in 2016 in which S. moorei was isolated alone or in mixed culture involving other anaerobes or both aerobic and anaerobic bacteria. Three cases were associated with the oral cavity, including a middle ear infection, a wound infection after total laryngectomy, and a mandibular abscess as a result of bisphosphonate therapy. In the other three patients, the sites of infection had no connections with the oral cavity and included chronic osteomyelitis of the tibia, a superinfection of cutaneous tuberculosis associated with hidradenitis suppurativa, and the isolation of S. moorei from the blood culture of a cachectic man with several comorbidities. Based on our findings, S. moorei does not appear to be that virulent of a bacterium; except for the case with bacteraemia, S. moorei was recovered as a co-pathogen in patients with several immunosuppressive predisposing factors. We highlight the finding that the routine use of MALDI-TOF MS in microbiology laboratories can in a timely and detailed manner identify members of mixed infections involving different anaerobic bacteria that may be rare and difficult-to-culture and identify species, such as S. moorei.