{Reference Type}: Journal Article {Title}: Clinical Outcomes After Anterior Cruciate Ligament Injury: Panther Symposium ACL Injury Clinical Outcomes Consensus Group. {Author}: Svantesson E;Hamrin Senorski E;Webster KE;Karlsson J;Diermeier T;Rothrauff BB;Meredith SJ;Rauer T;Irrgang JJ;Spindler KP;Ma CB;Musahl V;The Panther Symposium Acl Injury Clinical Outcomes Consensus Group ;Fu FH;Ayeni OR;Della Villa F;Della Villa S;Dye S;Ferretti M;Getgood A;Järvelä T;Kaeding CC;Kuroda R;Lesniak B;Marx RG;Maletis GB;Pinczewski L;Ranawat A;Reider B;Seil R;van Eck C;Wolf BR;Yung P;Zaffagnini S;Hao Zheng M; {Journal}: Orthop J Sports Med {Volume}: 8 {Issue}: 7 {Year}: Jul 2020 {Factor}: 3.401 {DOI}: 10.1177/2325967120934751 {Abstract}: A stringent outcome assessment is a key aspect of establishing evidence-based clinical guidelines for anterior cruciate ligament (ACL) injury treatment. To establish a standardized assessment of clinical outcome after ACL treatment, a consensus meeting including a multidisciplinary group of ACL experts was held at the ACL Consensus Meeting Panther Symposium, Pittsburgh, Pennsylvania, USA, in June 2019. The aim was to establish a consensus on what data should be reported when conducting an ACL outcome study, what specific outcome measurements should be used, and at what follow-up time those outcomes should be assessed. The group reached consensus on 9 statements by using a modified Delphi method. In general, outcomes after ACL treatment can be divided into 4 robust categories: early adverse events, patient-reported outcomes (PROs), ACL graft failure/recurrent ligament disruption, and clinical measures of knee function and structure. A comprehensive assessment after ACL treatment should aim to provide a complete overview of the treatment result, optimally including the various aspects of outcome categories. For most research questions, a minimum follow-up of 2 years with an optimal follow-up rate of 80% is necessary to achieve a comprehensive assessment. This should include clinical examination, any sustained reinjuries, validated knee-specific PROs, and health-related quality of life questionnaires. In the midterm to long-term follow-up, the presence of osteoarthritis should be evaluated. This consensus paper provides practical guidelines for how the aforementioned entities of outcomes should be reported and suggests the preferred tools for a reliable and valid assessment of outcome after ACL treatment.