{Reference Type}: Letter {Title}: Recombinant protein targeting and opsonizing spike glycoprotein for enhancing SARS-CoV-2 phagocytosis. {Author}: Khattabi L; {Journal}: Med Hypotheses {Volume}: 143 {Issue}: 0 {Year}: Oct 2020 {Factor}: 4.411 {DOI}: 10.1016/j.mehy.2020.110108 {Abstract}: The present hypothesis suggests an innovative therapeutic strategy to cease Covid 19 infection. It is based on the inhibition of Spike glycoprotein and ACE-2 receptor interaction that provides the entry of virus in human host cells, by targeting the S protein with a recombinant molecule made of the ACE-2 receptor ectodomain and an opsonin, the formed complex would enhance its phagocytosis.