{Reference Type}: Journal Article
{Title}: Is radial scar on core needle biopsy a risk factor for malignancy? A single-center retrospective review and implications for management.
{Author}: Woodward SG;Nimtz K;Hookim K;Sevrukov AB;Tsangaris TN;Willis A;Berger AC;Lazar M;
{Journal}: Breast J
{Volume}: 26
{Issue}: 10
{Year}: 10 2020
{Factor}: 2.269
{DOI}: 10.1111/tbj.13975
{Abstract}: Reported upgrade rate to malignancy of radial scars (RS) ranges widely (0%-40%) making management controversial.<BR>A retrospective chart review was performed on patients with RS on core needle biopsy (CNB). Upgrade rates to malignancy and atypia on surgical excision were evaluated.<BR>Of 127 patients with RS on CNB, 53 were excluded due to malignancy or missing records. Of 74 patients reviewed, 52 (70.3%) had surgical excision with four (7.7%) upgraded to malignancy. Eight patients (10.8%) had atypia with RS on CNB with two (25%) upgraded to malignancy. When isolated RS was on CNB, 2 of 44 (4.5%) upgraded to malignancy while 15 of 44 (34%) had atypia on excision. Of 22 patients (29.7%) who did not have excision, zero developed cancer.<BR>We found higher than expected upgrade rates of isolated RS to atypia which can alter management. Additionally, 25% of RS with atypia upgraded to malignancy suggesting these patients are at higher risk.