{Reference Type}: Case Reports
{Title}: Endometriosis-associated Clear Cell Carcinoma of the Abdominal Wall After Caesarean Section: A Case Report and Review of the Literature.
{Author}: Giannella L;Serri M;Maccaroni E;DI Giuseppe J;Carpini GD;Berardi R;Sopracordevole F;Ciavattini A;
{Journal}: In Vivo
{Volume}: 34
{Issue}: 4
{Year}: Jul-Aug 2020
{Factor}: 2.406
{DOI}: 10.21873/invivo.12021
{Abstract}: <B>OBJECTIVE: </B>Clear cell carcinoma of the abdominal wall is a sporadic event. To date, about thirty cases have been reported in the literature. This article provides a case report and literature review of an infrequent occurrence with poor prognosis.<BR><B>METHODS: </B>A 45-year-old woman with pelvic pain and an abdominal mass came to our attention. Her medical history was notable for two previous cesarean sections. Physical examination revealed a smooth, multilocular mass measuring about 20 cm, arising from the previous surgical scar. Histology revealed clear-cell carcinoma resulting from the transformation of abdominal wall endometriosis. Given the disease extent, the patient underwent front-line chemotherapy. After several and multiple chemotherapy regimens, there was a disease progression that resulted in the death of the patient in 7 months. The literature review showed that a previous cesarean section was present in 91% of cases. Besides, approximately 26.5% of women died within 12 months of being diagnosed. The mean age of women was 45.88 years, while the average size of the lesion was 11 cm.<BR><B>CONCLUSIONS: </B>Clear cell carcinoma is a rare but occurring event. Middle-aged women showing an abdominal wall mass in close relation with a surgical scar from a previous cesarean section must be promptly investigated. Treatment options usually include surgery and chemotherapy with poor results.