{Reference Type}: Journal Article
{Title}: Diagnosing cardiac amyloidosis in every-day practice: A practical guide for the cardiologist.
{Author}: Papathanasiou M;Carpinteiro A;Rischpler C;Hagenacker T;Rassaf T;Luedike P;
{Journal}: Int J Cardiol Heart Vasc
{Volume}: 28
{Issue}: 0
{Year}: Jun 2020
暂无{DOI}: 10.1016/j.ijcha.2020.100519
{Abstract}: Cardiac amyloidosis (CA) has emerged as a previously underestimated cause of heart failure and mortality. Underdiagnosis resulted mainly from unawareness of the true disease prevalence and the non-specific symptoms of the disease. CA results from extracellular deposition of misfolded protein fibrils, commonly derived from transthyretin (ATTR) or immunoglobulin light chains (AL). A significant proportion of older patients with heart failure and other extracardiac manifestations suffer from ATTR-CA, whereas AL-CA is still considered a rare disease. This article provides an overview of CA with a special focus on current and emerging diagnostic modalities. Furthermore, we provide a diagnostic algorithm for the evaluation of patients with suspected CA in every-day practice.