{Reference Type}: Journal Article {Title}: Study of Janus Amphiphilic Graphene Oxide as a High-Performance Shale Inhibitor and Its Inhibition Mechanism. {Author}: Lv K;Huang P;Zhou Z;Wei X;Luo Q;Huang Z;Yan H;Jia H; {Journal}: Front Chem {Volume}: 8 {Issue}: 0 {Year}: 2020 {Factor}: 5.545 {DOI}: 10.3389/fchem.2020.00201 {Abstract}: Janus amphiphilic graphene oxide (JAGO), modified by dodecylamine on one side of graphene oxide (GO), was investigated for its novel use as a shale inhibitor. JAGO was synthesized by the Pickering emulsion template technology and was characterized by the Fourier-transform infrared spectra, UV-vis spectra, and transmission electron microscopy. Compared to KCl (5%), polyether diamine (2%), and pristine GO (0.2%), JAGO's highest shale recovery rate (75.2% at 80°C) and lowest swelling height of Mt-pellets (2.55 mm, 0.2%) demonstrated its excellent inhibitive property. Furthermore, JAGO acted as a perfect plugging agent and greatly reduced filtration loss. Based on the results of X-ray diffraction, contact angle measurements, and pressure transmission tests, we proposed that the 2D nano-sheet amphiphilic structure of JAGO, which enabled it to be effective both in chemical inhibition and physical plugging, was responsible for its remarkable inhibition performances.