{Reference Type}: Journal Article
{Title}: [Effects of caudal block in pediatric surgical patients: a randomized clinical trial].
{Author}: Benka AU;Pandurov M;Galambos IF;Rakić G;Vrsajkov V;Drašković B;
{Journal}: Braz J Anesthesiol
{Volume}: 70
{Issue}: 2
{Year}: Mar 2020 0
暂无{DOI}: 10.1016/j.bjan.2019.12.003
{Abstract}: <B>BACKGROUND: </B>Surgery generates a neuroendocrine stress response, resulting in undesirable hemodynamic instability, alterations in metabolic response and malfunctioning of the immune system.<BR><B>OBJECTIVE: </B>The aim of this research was to determine the effectiveness of caudal blocks in intra- and postoperative pain management and in reducing the stress response in children during the same periods.<BR><B>METHODS: </B>This prospective, randomized clinical trial included 60 patients scheduled for elective herniorrhaphy. One group (n = 30) received general anesthesia and the other (n = 30) received general anesthesia with a caudal block. Hemodynamic parameters, drug consumption and pain intensity were measured. Blood samples for serum glucose and cortisol level were taken before anesthesia induction and after awakening the patient.<BR><B>RESULTS: </B>Children who received a caudal block had significantly lower serum glucose (p < 0.01), cortisol concentrations (p < 0.01) and pain scores 3 hours (p = 0.002) and 6 hours (p = 0.003) after the operation, greater hemodynamic stability and lower drug consumption. Also, there were no side effects or complications identified in that group.<BR><B>CONCLUSIONS: </B>The combination of caudal block with general anesthesia is a safe method that leads to less stress, greater hemodynamic stability, lower pain scores and lower consumption of medication.