{Reference Type}: Journal Article {Title}: Efficacy and Safety of Endoscopic Sleeve Gastroplasty at Mid Term in the Management of Overweight and Obese Patients: a Systematic Review and Meta-Analysis. {Author}: de Miranda Neto AA;de Moura DTH;Ribeiro IB;Khan A;Singh S;da Ponte Neto AM;Madruga Neto AC;do Monte Junior ES;Tustumi F;Bernardo WM;de Moura EGH; {Journal}: Obes Surg {Volume}: 30 {Issue}: 5 {Year}: May 2020 {Factor}: 3.479 {DOI}: 10.1007/s11695-020-04449-9 {Abstract}: BACKGROUND: Endoscopic sleeve gastroplasty (ESG) has emerged as a promising technique in endoscopic bariatric and metabolic therapies (EBMTs). We aimed to perform a systematic review and meta-analysis to provide an update on its efficacy and safety.
METHODS: This is a systematic review and meta-analysis was performed following the PRISMA guidelines. MEDLINE, Cochrane, EMBASE, and LILACS were searched to identify the studies related to ESG.
RESULTS: Eleven studies with a total of 2170 patients were included. The average BMI pre-ESG was 35.78 kg/m2. Pooled mean %TWL observed at 6, 12, and 18 months was 15.3%, 16.1%, and 16.8% respectively. Pooled mean %EWL at 6, 12, and 18 months was 55.8%, 60%, and 73% respectively. No procedure-related mortality was reported.
CONCLUSIONS: ESG is a safe and effective procedure for primary obesity therapy with promising short- and mid-term results.