{Reference Type}: Journal Article {Title}: In-hospital cardiac arrest and preceding National Early Warning Score (NEWS): A retrospective case-control study. {Author}: SpÄngfors M;Molt M;Samuelson K; {Journal}: Clin Med (Lond) {Volume}: 20 {Issue}: 1 {Year}: 01 2020 {Factor}: 5.41 {DOI}: 10.7861/clinmed.2019-0137 {Abstract}: We aimed to describe and evaluate the National Early Warning Score (NEWS) in the 24 hours preceding an in-hospital cardiac arrest among general somatic ward patients.The 24 hours preceding the in-hospital cardiac arrest were divided into four timespans and analysed by a medical record review of 127:254 matched case-control patients. The median NEWS ranged from 3 (2-6) to 6 (3-9) points for cases vs 1 (0-3) to 1 (0-3) point for controls. The proportion of cases ranged from 23-45% at high risk vs 3-6% for controls. The NEWS high-risk category was associated with an increase of 3.17 (95% confidence interval (CI) 1.66-6.04) to 4.43 (95% CI 2.56-7.67) in odds of in-hospital cardiac arrest compared to the low-risk category.NEWS, with its intuitive and for healthcare staff easy to interpret risk classification, is suitable for discriminating deteriorating patients with major deviating vital signs scoring high risk on NEWS.