{Reference Type}: Case Reports
{Title}: False-negative result of serum cryptococcal antigen lateral flow assay in an HIV-infected patient with culture-proven cryptococcaemia.
{Author}: Borges MASB;Araújo Filho JA;Soares RBA;Vidal JE;Turchi MD;
{Journal}: Med Mycol Case Rep
{Volume}: 26
{Issue}: 0
{Year}: Dec 2019
暂无{DOI}: 10.1016/j.mmcr.2019.10.009
{Abstract}: The detection of cryptococcal capsular antigen (CrAg) is very sensitive and specific, however false-negative results have been reported, mostly in cerebrospinal fluid. We report the case of an HIV-infected patient with CD4 = 42 cells/mL, asthenic, negative serum CrAg lateral flow assay (LFA) and culture-proven cryptococcaemia. Despite the high accuracy of LFA, false-negative result is possible. Careful clinical evaluation and close follow-up are relevant.