{Reference Type}: Journal Article
{Title}: High-Resolution Imaging of Retinal Vasculitis by Flood Illumination Adaptive Optics Ophthalmoscopy: A Follow-up Study.
{Author}: Errera MH;Laguarrigue M;Rossant F;Koch E;Chaumette C;Fardeau C;Westcott M;Sahel JA;Bodaghi B;Benesty J;Paques M;
{Journal}: Ocul Immunol Inflamm
{Volume}: 28
{Issue}: 8
{Year}: Nov 2020 16
{Factor}: 3.728
{DOI}: 10.1080/09273948.2019.1646773
{Abstract}: Purpose: To monitor perivascular sheathing during the course of retinal vasculitis by flood illumination adaptive optics ophthalmoscopy (AOO). Methods: Perivenous sheathing and venous diameters were quantitatively analyzed by semi-automatic segmentation of AOO images in 12 eyes of treatment-naive patients with retinal vasculitis. Results: The width of venous sheathing ranged from 45 to 225 µm (mean 101.0 µm ± 54.3). In 10 cases, the underlying vein showed focal narrowing (mean ± SD 14% ± 10). Focal narrowing of arteries was also present in one eye. At presentation, width of sheathing and vessel diameters were not correlated with fluorescein leakage. During follow-up, 5 eyes showed an increase in vein diameter or resolution of narrowing and in 10 eyes a thinning of vascular sheathing was observed (p= .003). Conclusions: Perivenous sheathing may be quantitatively analyzed and monitored by AOO. AOO may therefore contribute to monitor vascular sheathing during posterior uveitis.