{Reference Type}: Journal Article
{Title}: Perspectives on Scedosporium species and Lomentospora prolificans in lung transplantation: Results of an international practice survey from ESCMID fungal infection study group and study group for infections in compromised hosts, and European Confederation of Medical Mycology.
{Author}: Rammaert B;Puyade M;Cornely OA;Seidel D;Grossi P;Husain S;Picard C;Lass-Flörl C;Manuel O;Le Pavec J;Lortholary O; ;
{Journal}: Transpl Infect Dis
{Volume}: 21
{Issue}: 5
{Year}: Oct 2019
暂无{DOI}: 10.1111/tid.13141
{Abstract}: <B>BACKGROUND: </B>Scedosporium species and Lomentospora prolificans (S/L) are the second most common causes of invasive mold infections following Aspergillus in lung transplant recipients.<BR><B>METHODS: </B>We assessed the current practices on management of S/L colonization/infection of the lower respiratory tract before and after lung transplantation in a large number of lung transplant centers through an international practice survey from October 2016 to March 2017.<BR><B>RESULTS: </B>A total of 51 respondents from 45 lung transplant centers (17 countries, 4 continents) answered the survey (response rate 58%). S/L colonization was estimated to be detected in candidates by 48% of centers. Only 18% of the centers used a specific medium to detect S/L colonization. Scedosporium spp. colonization was a contraindication to transplantation in 10% of centers whereas L prolificans was a contraindication in 31%; 22% of centers declared having had 1-5 recipients infected with S/L in the past 5 years.<BR><B>CONCLUSIONS: </B>This survey gives an overview of the current practices regarding S/L colonization and infection in lung transplant centers worldwide and underscores the need of S/L culture procedure standardization before implementing prospective studies.