{Reference Type}: Journal Article
{Title}: Clozapine-induced interstitial nephritis in a patient with schizoaffective disorder in the forensic setting: a case report and review of the literature.
{Author}: McLoughlin C;Cooney C;Mullaney R;
{Journal}: Ir J Psychol Med
{Volume}: 0
{Issue}: 0
{Year}: Jun 2019 21
暂无{DOI}: 10.1017/ipm.2019.24
{Abstract}: We present a rare case of Acute Interstitial Nephritis (AIN) that occurred following a re-trial of clozapine in a 56-year-old lady with schizoaffective disorder. On initial trial of clozapine, this patient felt generally unwell with respiratory symptoms. Her inflammatory markers were raised and her renal function showed a mild, transient deterioration which normalised on the day of cessation of clozapine. Two years later, clozapine was re-trialled due the refractory nature of her psychiatric symptoms. She subsequently developed renal failure and AIN was confirmed by renal biopsy. Renal function improved after cessation of clozapine; however, she never fully regained normal renal function.