{Reference Type}: Case Reports
{Title}: Late-onset sepsis and encephalopathy after bicycle-spoke injury: a case report.
{Author}: Takemoto R;Motomura Y;Kaku N;Ichimiya Y;Muraoka M;Kanno S;Tanaka T;Sakai Y;Maehara Y;Ohga S;
{Journal}: BMC Infect Dis
{Volume}: 19
{Issue}: 1
{Year}: May 2019 28
{Factor}: 3.667
{DOI}: 10.1186/s12879-019-4082-4
{Abstract}: <B>BACKGROUND: </B>Bicycle-spoke injuries rarely cause late complications of infection, including sepsis and sepsis-associated encephalopathy, with appropriate treatments.<BR><B>METHODS: </B>We experienced a 2-year-old girl who developed the signs of encephalopathy with fever 6 months after a spoke-injury. On admission, the injured skin was inflamed with cellulitis. The blood culture was positive for methicillin-sensitive Staphylococcus aureus. Electroencephalogram showed diffuse slow-wave activity. Diffusion-weighted magnetic resonance imaging detected a high-intensity lesion with decreased diffusivity at the right frontal cortex. She received immunoglobulin and combined antibiotics treatments in the intensive care unit, and successfully overcame the sepsis-associated encephalopathy without neurological impairments.<BR><B>CONCLUSIONS: </B>This is the first report demonstrating that sepsis and its associated encephalopathy occurs in a remote period after the bicycle-spoke injury.