{Reference Type}: Journal Article
{Title}: Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c.
{Author}: Lee C;
{Journal}: Mol Cell Oncol
{Volume}: 6
{Issue}: 2
{Year}: 2019
暂无{DOI}: 10.1080/23723556.2018.1549464
{Abstract}: Cellular stress response is coordinated through the communication between mitochondria and the nucleus. However, whereas mitochondria are regulated by nuclear-encoded proteins, the nucleus was considered ungoverned by mitochondrial-encoded factors. We recently reported that a mitochondrial-encoded peptide directly regulates the nuclear genome upon cellular stress, indicating an integrated bi-genomic cross-communication mechanism.