{Reference Type}: Journal Article
{Title}: Vitamin A and Pregnancy: A Narrative Review.
{Author}: Bastos Maia S;Rolland Souza AS;Costa Caminha MF;Lins da Silva S;Callou Cruz RSBL;Carvalho Dos Santos C;Batista Filho M;
{Journal}: Nutrients
{Volume}: 11
{Issue}: 3
{Year}: Mar 2019 22
{Factor}: 6.706
{DOI}: 10.3390/nu11030681
{Abstract}: Vitamin A is a crucial micronutrient for pregnant women and their fetuses. In addition to being essential for morphological and functional development and for ocular integrity, vitamin A exerts systemic effects on several fetal organs and on the fetal skeleton. Vitamin A requirements during pregnancy are therefore greater. Vitamin A deficiency (VAD) remains the leading cause of preventable blindness in the world. VAD in pregnant women is a public health issue in most developing countries. In contrast, in some developed countries, excessive vitamin A intake during pregnancy can be a concern since, when in excess, this micronutrient may exert teratogenic effects in the first 60 days following conception. Routine prenatal vitamin A supplementation for the prevention of maternal and infant morbidity and mortality is not recommended; however, in regions where VAD is a public health issue, vitamin A supplementation is recommended to prevent night blindness. Given the importance of this topic and the lack of a complete, up-to-date review on vitamin A and pregnancy, an extensive review of the literature was conducted to identify conflicting or incomplete data on the topic as well as any gaps in existing data.