{Reference Type}: Case Reports
{Title}: Neuropathic diabetic foot ulcers treated with cerium dioxide nanoparticles: A case report.
{Author}: Kobyliak N;Abenavoli L;Kononenko L;Kyriienko D;Spivak M;
{Journal}: Diabetes Metab Syndr
{Volume}: 13
{Issue}: 1
{Year}: Jan 2019 0
暂无{DOI}: 10.1016/j.dsx.2018.08.027
{Abstract}: Wound healing in diabetes is frequently impaired and its treatment remains a challenge. The ability of topical application of cerium (Ce) dioxide nanoparticles (CNPs) to accelerate wound healing in an animal model provides a rationale to develop this technology for use in humans affected by traumatic injury, diabetes and burns. We first described a case report of successful topical treatment of neuropathic diabetic foot ulcers with novel gel containing CNPs. The CNPs has bacteriostatic activity, anti-inflammatory properties and can penetrated into the wound tissue and reduced oxidative damage therefore protect regenerative tissue, suggesting a therapeutic potential for topical treatment of diabetic foot ulcers.