{Reference Type}: Journal Article
{Title}: Glycolysis Inhibitors Monoiodoacetate and 2-Deoxyglucose as Antitumor Agents: Experimental Study on Lewis Lung Carcinoma Model.
{Author}: Korshunov DA;Klimov IA;Ivanov VV;Kondakova IV;
{Journal}: Bull Exp Biol Med
{Volume}: 165
{Issue}: 5
{Year}: Sep 2018
{Factor}: 0.737
{DOI}: 10.1007/s10517-018-4244-1
{Abstract}: Antitumor effects of glycolysis inhibitors monoiodoacetate and 2-deoxyglucose were studied on Lewis lung carcinoma model. Monoiodoacetate exhibited antitumor and antimetastatic activities, being not inferior of methotrexate (reference drug); however, the preparation also demonstrated high systemic toxicity. 2-Deoxyglucose exhibited only antitumor effect, while its antimetastatic activity did not differ from the result in the group without treatment.